Add to ORKGAbstract: Zolpidem modifi ed-release (MR) is the fi rst hypnotic agent to be marketed in an extended-release formulation. Zolpidem MR is a two-layered, biphasic release tablet indicated for the management of induction of sleep and sleep maintenance. The pharmacokinetics of the drug are similar to those of immediate-release zolpidem. Two double-blind, placebo-controlled, parallel-group trials demonstrated effi cacy in adults and elderly patients treated with zolpidem MR for 3 weeks without signifi cant impairment in next-day psychomotor functioning. The most common adverse effects with zolpidem MR were dizziness, somnolence, and headache. A starting dose of zolpidem MR 12.5 mg is recommended for adults and 6.25 mg for elderly patients
Zolpidem is a hypnotic drug with rapid -onset and short duration of action. It is popularly used for...
Zolpidem is a non-benzodiazepine property which binds selectively to the α1-GABAA receptors, and has...
Patients with disorders of consciousness (DOC) have profound functional limitations with few treatme...
Insomnia is linked to fatigue, distractibility, mood instability, decreased satisfaction, and overal...
The safety and efficacy of treatment with zolpidem for one month were assessed in an open evaluation...
The efficacy of zolpidem, a non benzodiazepine hypnotic agent with a short elimination half life, wa...
Zolpidem has been reported as an “awakening drug” in some patients with disorders of consciousness ...
A multicentre post-marketing surveillance study was conducted in Switzerland in routine practice and...
Insomnia is a highly prevalent sleep disorder that frequently occurs in its acute form and occurs at...
Background/significance: Benzodiazepines, first generation antihistamines, sedative hypnotics, and t...
Background: Being a nonbenzodiazepine, zolpidem is believed to have a favorable side-effect profile ...
Insomnia is a prevalent disorder with deleterious effects such as decreased quality of life, and a p...
zolpidem is an imidazopyridine sedative-hypnotic drug used to treat insomnia.this is mediated via zo...
In a simulation study evaluating the residual effects of taking a single night-time dose of hypnotic...
Zolpidem is a non-benzodiazepine sedative hypnotic that binds to the benzodiazepine binding site on ...
Zolpidem is a hypnotic drug with rapid -onset and short duration of action. It is popularly used for...
Zolpidem is a non-benzodiazepine property which binds selectively to the α1-GABAA receptors, and has...
Patients with disorders of consciousness (DOC) have profound functional limitations with few treatme...
Insomnia is linked to fatigue, distractibility, mood instability, decreased satisfaction, and overal...
The safety and efficacy of treatment with zolpidem for one month were assessed in an open evaluation...
The efficacy of zolpidem, a non benzodiazepine hypnotic agent with a short elimination half life, wa...
Zolpidem has been reported as an “awakening drug” in some patients with disorders of consciousness ...
A multicentre post-marketing surveillance study was conducted in Switzerland in routine practice and...
Insomnia is a highly prevalent sleep disorder that frequently occurs in its acute form and occurs at...
Background/significance: Benzodiazepines, first generation antihistamines, sedative hypnotics, and t...
Background: Being a nonbenzodiazepine, zolpidem is believed to have a favorable side-effect profile ...
Insomnia is a prevalent disorder with deleterious effects such as decreased quality of life, and a p...
zolpidem is an imidazopyridine sedative-hypnotic drug used to treat insomnia.this is mediated via zo...
In a simulation study evaluating the residual effects of taking a single night-time dose of hypnotic...
Zolpidem is a non-benzodiazepine sedative hypnotic that binds to the benzodiazepine binding site on ...
Zolpidem is a hypnotic drug with rapid -onset and short duration of action. It is popularly used for...
Zolpidem is a non-benzodiazepine property which binds selectively to the α1-GABAA receptors, and has...
Patients with disorders of consciousness (DOC) have profound functional limitations with few treatme...